Catalog #500114
| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 500114 | 100 ug | $120.00 | ||
| 500114 | 1 mg | $150.00 | ||
| 500114 | 5 mg | $350.00 | ||
| 500114 | 25 mg | $900.00 |
The in vivo grade recombinant human IgG1 Fc protein (hIgG1 Fc, Glu 99 - Lys 330 of the constant region of the IgG1 heavy chain, Accession # P01857-1) was produced in mammalian cells and purified by protein A. The hIgG1 Fc protein includes the CH2 (111-223) and CH3 (224-330) domains of the heavy chain constant region as well as the hinge region (99-110) before the CH2 domain. The C103S version of the hIgG1 Fc protein is also available. The C103S substitution prevents improper cysteine bond formation in the absence of a light chain.
| Isotype | Human IgG1 |
|---|---|
| Format | Liquid |
| Formluation | PBS, pH 7.4 |
| Sterility | 0.2 µm filtered |
| Clonality | Recombinant |
| Conjugation | Unconjugated |
| Host | Mammalian cells |
| Purity | >95% by reducing SDS-PAGE |
| Endotoxin | < 1.0 EU/mg (LAL assay) |
| Grade | In vivo ready (RUO) |
| Application | ELISA; WB; Flow cytometry; IHC; functional assays |
| Purification | Protein A |
| Storage Conditions | 2-8 °C, Avoid freeze / thaw cycle |
| Shelf Life | 6 months |
| Regulatory Status | RUO |